Cryo-Transfer Holders

Ideal for low-temperature transfer of frozen-hydrated specimens.

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Advantages: 

Cryo-transfer holders are used in applications that require low-temperature transfer and observation of frozen-hydrated specimens for cryo-electron microscopy (cryo-EM).

  • Cryo-workstation provides protected environment for loading specimen into holder
  • Cryo-shield encapsulates frozen-hydrated specimen to protect it from contamination during atmospheric transfers from cryo-workstation to the transmission electron microscope (TEM)
Model 
Min. operating
temp.
Beryllium
cradle
Specimen positioning
Specimen securing
Motorized control
Multiple specimen
Less than
-170 °C
 
α Tilt
Quickload 
(ULP)
Clipring (STP)
 
 
910
Less than
-170 °C
 
α Tilt
Splitring
 
1
915
Less than
-170 °C
α, β Tilt
Hexring®
β Tilt
 
1 Two specimen positions are available in holders for the Hitachi and Zeiss TEMs. Three specimen positions are available in holders for FEI, JEOL, and Topcon TEMs.

Publications

Nature Methods
2023

Li, W.; Lu, J.; Xiao, K.; Zhou, M.; Li, Y.; Zhang, X.; Li, Z.; Gu, L.; Xu, X.; Gui, Q.; Xu, T.; Ji, W.

Scientific Reports
2022

Krishnaswamy, S. R.; Gabrovski, I. A.; Patmanidis, I.; Stuart, M. C. A.; de Vries A. H.; Pshenichnikov, M. S.

Science
2022

Zhang, Z.; Li, Y.; Xu, R.; Zhou, W.; Li, Y.; Oyakhire, S. T.; Wu, Y.; Xu, J.; Wang, H.; Yu, Z.; Boyle, D. T.; Huang, W.; Ye, Y.; Chen, H.; Wan, J.; Bao, Z.; Chiu, W.; Cui, Y.

Resources:

 

Models 698, 910, 915

Datasheets

Elsa Cryo-Transfer Holder, model 698
Multi-Specimen Single Tilt Cryo-Transfer Holder, model 910
Double Tilt Liquid Nitrogen Cryo-Transfer Holder, model 915

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